ACTION
Memory tonic was formulated to synergistically enhance the different functions of memory. The ingredients have been mixed in different ratios for maximum performance.
WHO SHOULD USE IT?
INGREDIENTS
Melissa officinalis, Rosmarinus officinalis,
Ginkgo biloba, Salvia officinalis, Centella asiatica, Panax Ginseng, Eleutherococcus senticosus, Thymus vulgaris, Zingiber officinale, Avena sativa and Withania somnifera.
RESEARCH
Ginkgo biloba is used to alleviate symptoms associated with cognitive deficits, e.g., decreased memory performance, lack of concentration, decreased alertness, tinnitus, and dizziness. Pharmacologic studies have shown that the therapeutic effect of ginkgo is based on several active constituents with vasoactive and free radical-scavenging properties (Soholm, B. 1998).
Active glycowithanolides of Withania somnifera have significant antioxidant function which is accomplished by increasing the activities of superoxide dismutase, catalase and glutathione peroxidase c (Bhattacharya, S.K., et al. 1997).
Withania somnifera has cognition-enhancing and memory-improving effects. These effects could be partly explained because extracts from the plant caused an increase in cortical muscarinic acetylcholine receptor capacity (Schliebs, R., et al. 1997).
Eriodicytol, a flavonoid in thyme was found to be antioxidative. It inhibited superoxide anion production in the xanthine/xanthine oxidase system and protected red cells against oxidative hemolysis
(Haraguchi, H. et al. 1996).
Phenolic glycosides in sage were found to have antioxidant property (Wang, M. et al. 1999).
The sesquiterpenes in Zingiber officinale
have specific effects against cold viruses.
Thyme is very effective in relaxing smooth muscles (Van Den Broucke, C.O, 1983). One of its constituents, thymol is a strong antiseptic.
In Alzheimer's disease, there is degeneration of cholinergic neurons in Meynert's and other brain stem nuclei. Salvia officinalis and Melissa officinalis have been found to have cholinergic activities (Perry, E.K. et al. 1998, 1999).
In a study, acetone extract of ginger at 100 mg/kg p.o.
significantly inhibited serotonin (5-HT) induced
hypothermia. The active responsible was found to be shogoal.
Shogoal, [6]-dehydrogingerdione, [8]- and [10]-gingerol
were also found to have an anticathartic action (Huang Q, et al. (1990).
REFERENCES
Bhattacharya, S.K., Ashok, Kumar Shibnath, Ghosal (1995). Effects of glycowithanolides from Withania somnifera on an animal model of Alzheimer's disease and perturbed central cholinergic markers of cognition in rats.
Phytotherapy Research. 9(2);110-113.
Bhattacharya, S.K., Satyan, K.S., Ghosal, S. ((1997). Antioxidant activity of glycowithanolides from Withania somnifera. Indian J.Exp.Biol.35(3);236-9
Haraguchi, H., Saito, T., Ishikawa, H., Date, H., Kataoka, S., Tamura, Y. and Mizutani, K. (1996).Antiperoxidative components in Thymus vulgaris.
Planta Med 62(3):217-21.
Schliebs, R., Liebmann, A., Bhattacharya, S.K., Kumar, A., Ghosal, S. and Bigl, V. (1997). Systemic administration of defined extracts from Withania somnifera (Indian Ginseng) and Shilajit differentially affects cholinergic but not glutamatergic and GABAergic markers in rat brain. Neurochem. Int. 30(2):181-90.
Soholm, B. (1998). Clinical improvement of memory and other cognitive functions by Ginkgo biloba: review of relevant literature. Adv. Ther. 15(1):54-65.
Huang Q, et al. (1990). The effect of ginger on serotonin
induced hypothermia and diarrhea.
Yakugaku Zasshi Dec;110(12):936-42
Perry, E.K., Pickering, A.T., Wang, W.W., Houghton, P.J. and Perry, N.S. (1998). Medicinal plants and Alzheimer's disease: Integrating ethnobotanical and contemporary scientific evidence. J. Altern. Complement. Med. 4(4):419-28.
Perry, E.K., Pickering, A.T., Wang, W.W., Houghton, P.J. and Perry, N.S. (1999).Medicinal plants and Alzheimer's disease: from ethnobotany to phytotherapy. J. Pharm. Pharmacol. 51(5):527-34.
Van Den Broucke, C.O, and Lemli, J.A. (1983). Spasmolytic activity of the flavonoids from Thymus vulgaris. Pharm. Weekbl. [Sci], 5(1):9-14
Wang, M., Shao, Y., Li, J., Zhu, N., Rangarajan, M., LaVoie, E.J. and Ho, C.T. (1999). Antioxidative phenolic glycosides from sage (Salvia officinalis). J. Nat. Prod. 62(3):454-6.
| These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. |